2018-12-07 15:51:002025-05-17 01:50:34
locus
BSU40900
BSU_40900
geneLength
516
519
outlinks
bsu
BSU40900
BSU_40900
Gene
Coordinates
4,198,886 → 4,199,404
4,198,886 4,199,404
The protein
Catalyzed reaction/ biological activity
SsbA inhibits ssDNA phosphorylase activity of [[protein|PnpA]] [Pubmed|21859751]
SsbA co-assembles onto [[protein|SsbB]]-coated ssDNA [Pubmed|22373918]
important for [[protein|RecA]] DNA repair center assembly by recruiting [[protein|RecO]] and [[protein|RecR]] to the [SW|replisome] [Pubmed|24891441]
[[protein|RecA]]-ATP in concert with [[protein|DprA]] and [[protein|SsbA]] catalyzes DNA strand exchange, with [[protein|SsbB]] as an accessory factor [Pubmed|25138221]
inhibits stable [[protein|RecA]] nucleation and polymerization on ssDNA [pubmed|28911099]
SsbA inhibits ssDNA phosphorylase activity of [[protein|PnpA]] [Pubmed|21859751]
SsbA co-assembles onto [[protein|SsbB]]-coated ssDNA [Pubmed|22373918]
important for [[protein|RecA]] DNA repair center assembly by recruiting [[protein|RecO]] and [[protein|RecR]] to the [SW|replisome] [Pubmed|24891441]
[[protein|RecA]]-ATP in concert with [[protein|DprA]] and [[protein|SsbA]] catalyzes DNA strand exchange, with [[protein|SsbB]] as an accessory factor [Pubmed|25138221]
inhibits stable [[protein|RecA]] nucleation and polymerization on ssDNA [pubmed|28911099]
the [[protein|SsbA]]-[[protein|DprA]] mediator loads [[protein|RecA]] onto any fragmented linear SPP1 ssDNA[pubmed|31876108]
The protein
Structure
[PDB|3VDY] (SsbB in complex with ssDNA, 63% identity, 87% similarity) [Pubmed|22373918]
[PDB|6BHX] (complex with ssDNA) [Pubmed|30472092]
[PDB|6BHW] [Pubmed|30472092]
References
Reviews
References
Original publications
The protein
[SW|Domains]
SSB domain (aa 1-104) (according to UniProt)